Important safety information IMPORTANT SAFETY INFORMATION

Full prescription information FULL PRESCRIBING INFORMATION

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address injection site reactions.

As you continue your treatment on KINERET® (anakinra), you may experience some skin-related injection site reactions (ISRs). Fortunately, there may be ways to help address them. Most people's reactions lessen or stop after the first month.1,* Of course, you can always speak to your healthcare provider and read the KINERET Prescribing Information.

*Injection-site reactions are the most common treatment-related issue associated with KINERET. In clinical studies, 71% of patients developed a reaction, typically within the first 4 weeks of therapy. Most reactions were mild, and typically lasted for 14 to 28 days.1


A burning, stinging sensation Bring KINERET to room temperature—even when you are in a hurry.
Swelling Cool the site with an ice pack or cold compress for a few minutes, both before and after injecting.
Rash or itching Apply a topical hydrocortisone or antihistamine cream to your skin after injecting.
Soreness Rotate sites. A diary or the KINERET Injection Tracker can help you remember which sites you used recently.
Redness or bruising Never inject into skin that is red, bruised or tender.

Reference: 1. KINERET [Prescribing Information]. Stockholm, Sweden: Swedish Orphan Biovitrum AB (publ).

Still have questions about injecting KINERET? Read the KINERET Prescribing Information, and/or ask your doctor.


KINERET® (anakinra) is a prescription medicine called an interleukin-1 receptor antagonist (IL-1Ra) used to:

  • Reduce the signs and symptoms and slow the damage of moderate to severe active rheumatoid arthritis (RA) in people aged 18 years and older when 1 or more other drugs for RA have not worked
  • Treat people with a form of Cryopyrin-Associated Periodic Syndromes (CAPS) called Neonatal-Onset Multisystem Inflammatory Disease (NOMID)

KINERET is not for children with Juvenile Rheumatoid Arthritis.


Who should not take KINERET?

People who are allergic to:

What information should I know before starting KINERET?

Before you use KINERET, tell your healthcare provider if you:

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. KINERET and other medicines may affect each other and cause serious side effects. Especially tell your healthcare provider if you take certain other medicines that affect your immune system called Tumor Necrosis Factor (TNF) blockers. Ask your healthcare provider for a list of these medicines if you are not sure. Know the medications you take. Keep a list of your medicines and show it to your healthcare provider and pharmacist when you get a new prescription.

What are the possible side effects of KINERET?

KINERET may cause serious side effects, including:

The most common side effects of KINERET include:

Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects of KINERET. For more information ask your healthcare provider or pharmacist.

Please see full Prescribing Information.